Global EditionASIA 中文雙語Fran?ais
    China
    Home / China / Health

    Pig kidney recipient good after 30 days

    By QIN FENG in Xi'an and ZOU SHUO | China Daily | Updated: 2025-04-10 08:57
    Share
    Share - WeChat

    Asia's first gene-edited pig kidney transplant patient has maintained stable kidney function for more than 30 days after surgery and has met the criteria for discharge, marking a milestone in China's xenotransplantation research and offering new hope for patients facing organ shortages, the hospital that performed the surgery said on Tuesday.

    Doctors at Xijing Hospital of Air Force Military Medical University in Xi'an, Shaanxi province, said the surgery was performed on March 6 by a multidisciplinary team led by Qin Weijun, director of the hospital's urology department, under the guidance of Dou Kefeng, an academician of the Chinese Academy of Sciences.

    The patient, a 69-year-old woman diagnosed with end-stage renal failure eight years ago, had limited treatment options — dialysis or a kidney transplant. However, due to her high sensitivity to human donor antigens, no compatible human kidney was available, leaving her reliant on dialysis.

    As of now, the transplanted kidney is functioning stably, with serum creatinine levels maintained between 66 and 110 micromoles per liter and daily urine output ranging from 1,800 to 2,600 milliliters, the hospital said. The patient's vital signs remain normal, confirming the procedure's initial success.

    To address critical challenges in xenotransplantation — immune rejection, coagulation dysfunction and zoonotic infection risks — the medical team implemented a three-pronged strategy: targeted immunosuppression, coagulation regulation and a comprehensive infection control protocol. More than 20 clinical departments collaborated through a joint diagnosis and treatment mechanism, conducting real-time monitoring and adjusting medication regimens dynamically.

    Qin said the team established a monitoring system encompassing immune response tracking, virus screening and coagulation parameter analysis to enable timely interventions.

    Dou emphasized the study's significance, calling it a "breakthrough" that "validates the clinical feasibility of xenotransplantation for patients with end-stage renal disease, providing crucial theoretical and technical foundations for future applications".

    While the patient has met discharge standards, her release date has not been determined due to ongoing management of existing conditions, including high blood pressure and cerebral infarction, the hospital said.

    The breakthrough is particularly relevant for China's healthcare system, where about 150,000 new end-stage renal disease patients are diagnosed annually, but fewer than 5 percent receive lifesaving transplants.

    The surgery marks the world's fifth such procedure and the first in Asia. It is also another clinical milestone for Xijing Hospital, which performed the world's first successful gene-edited pig-to-brain-dead recipient xenogenetic orthotropic whole liver transplant on Jan 7.

    Top
    BACK TO THE TOP
    English
    Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
    License for publishing multimedia online 0108263

    Registration Number: 130349
    FOLLOW US
     
    超清无码无卡中文字幕| 久久精品中文字幕无码绿巨人| 特级无码毛片免费视频尤物| 熟妇人妻久久中文字幕| 人妻中文字系列无码专区| 亚洲乱码中文字幕综合234| 亚洲中文字幕伊人久久无码| 无码人妻久久一区二区三区免费丨 | AV大片在线无码永久免费| 国产又爽又黄无码无遮挡在线观看| 中文字幕人妻色偷偷久久| 无码精品人妻一区二区三区中| 国产成人无码一区二区在线观看| 人妻精品久久久久中文字幕一冢本 | 精品久久久久久无码中文字幕| 无码av不卡一区二区三区| 无码精品A∨在线观看| 最新国产精品无码| 日日摸夜夜添无码AVA片| 中文字幕av在线| 中文字幕14页影音先锋| 2022中文字幕在线| 国产日韩精品中文字无码| 亚洲中文字幕无码久久精品1| 韩国中文字幕毛片| 中文无码久久精品| 欧美日韩久久中文字幕 | 天堂√最新版中文在线天堂| 中文字幕丰满乱孑伦无码专区| 免费a级毛片无码免费视频| 成人无码小视频在线观看| 少妇人妻无码精品视频app| 日韩免费无码视频一区二区三区| 亚洲AV永久青草无码精品| 日韩精品久久无码中文字幕| 日韩乱码人妻无码系列中文字幕| 免费人妻无码不卡中文字幕系| 成人无码午夜在线观看| 免费A级毛片无码无遮挡| 无码国内精品久久人妻麻豆按摩 | 黑人无码精品又粗又大又长 |