Global EditionASIA 中文雙語Fran?ais
    China
    Home / China / Health

    Pig kidney recipient good after 30 days

    By QIN FENG in Xi'an and ZOU SHUO | China Daily | Updated: 2025-04-10 08:57
    Share
    Share - WeChat

    Asia's first gene-edited pig kidney transplant patient has maintained stable kidney function for more than 30 days after surgery and has met the criteria for discharge, marking a milestone in China's xenotransplantation research and offering new hope for patients facing organ shortages, the hospital that performed the surgery said on Tuesday.

    Doctors at Xijing Hospital of Air Force Military Medical University in Xi'an, Shaanxi province, said the surgery was performed on March 6 by a multidisciplinary team led by Qin Weijun, director of the hospital's urology department, under the guidance of Dou Kefeng, an academician of the Chinese Academy of Sciences.

    The patient, a 69-year-old woman diagnosed with end-stage renal failure eight years ago, had limited treatment options — dialysis or a kidney transplant. However, due to her high sensitivity to human donor antigens, no compatible human kidney was available, leaving her reliant on dialysis.

    As of now, the transplanted kidney is functioning stably, with serum creatinine levels maintained between 66 and 110 micromoles per liter and daily urine output ranging from 1,800 to 2,600 milliliters, the hospital said. The patient's vital signs remain normal, confirming the procedure's initial success.

    To address critical challenges in xenotransplantation — immune rejection, coagulation dysfunction and zoonotic infection risks — the medical team implemented a three-pronged strategy: targeted immunosuppression, coagulation regulation and a comprehensive infection control protocol. More than 20 clinical departments collaborated through a joint diagnosis and treatment mechanism, conducting real-time monitoring and adjusting medication regimens dynamically.

    Qin said the team established a monitoring system encompassing immune response tracking, virus screening and coagulation parameter analysis to enable timely interventions.

    Dou emphasized the study's significance, calling it a "breakthrough" that "validates the clinical feasibility of xenotransplantation for patients with end-stage renal disease, providing crucial theoretical and technical foundations for future applications".

    While the patient has met discharge standards, her release date has not been determined due to ongoing management of existing conditions, including high blood pressure and cerebral infarction, the hospital said.

    The breakthrough is particularly relevant for China's healthcare system, where about 150,000 new end-stage renal disease patients are diagnosed annually, but fewer than 5 percent receive lifesaving transplants.

    The surgery marks the world's fifth such procedure and the first in Asia. It is also another clinical milestone for Xijing Hospital, which performed the world's first successful gene-edited pig-to-brain-dead recipient xenogenetic orthotropic whole liver transplant on Jan 7.

    Top
    BACK TO THE TOP
    English
    Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
    License for publishing multimedia online 0108263

    Registration Number: 130349
    FOLLOW US
     
    日日摸夜夜爽无码毛片精选| 无码毛片视频一区二区本码 | 亚洲AV无码一区二三区| 无码人妻丰满熟妇区96| 久久ZYZ资源站无码中文动漫| 狠狠噜天天噜日日噜无码| 亚洲成A人片在线观看中文| 日本公妇在线观看中文版 | 久久国产三级无码一区二区| 亚洲韩国精品无码一区二区三区 | 中文字幕天天躁日日躁狠狠躁免费| 成在线人AV免费无码高潮喷水| 亚洲AV永久无码精品网站在线观看 | 人妻无码精品久久亚瑟影视| 午夜不卡无码中文字幕影院| 亚洲av无码不卡私人影院| 2019亚洲午夜无码天堂| 无码AV岛国片在线播放| 国产AV无码专区亚洲AV手机麻豆| 最好看2019高清中文字幕| 久久国产高清字幕中文| 中文无码成人免费视频在线观看| 日韩电影无码A不卡| 国产精品无码永久免费888| 国产∨亚洲V天堂无码久久久| 熟妇人妻AV无码一区二区三区| 中文字幕av无码一区二区三区电影| 国产成人无码免费看视频软件| 玖玖资源站中文字幕在线| 亚洲欧美成人久久综合中文网 | 中文字幕在线观看国产| 中文字幕日韩理论在线| 最好看的电影2019中文字幕 | 日韩AV无码久久一区二区| 无码人妻AV免费一区二区三区| 手机永久无码国产AV毛片| Aⅴ精品无码无卡在线观看| 人妻少妇精品无码专区动漫 | 亚洲韩国—中文字幕| 最近免费中文字幕大全免费| 中文字幕亚洲一区二区va在线|